Mr. Garrison tries to make his longtime dream of becoming a woman come true. When he is finally able to revel in womanhood, the South Park residents also begin to tap into their own sensitive side as well. Meanwhile, Kyle has difficulty coming to terms with the possibility that Jews have no real skills in basketball.
The residents of South Park enlist Cartman's help in finally eliminating all of the hippies for good.
The boys decide to become talent agents when they realize that agents get 10% of their clients' earnings, but only manage to land one client, who is soon stolen by a rival agency. After soon finding themselves a new client, however, they decide to shoehorn her into the world of reality TV to make some quick money.
When Kenny is the only one in the group to get the latest and coolest portable video game system, the news sends Cartman into a tailspin of resentment and jeopardizes their chances of being best friends forever.
The boys contemplate doing their part to help lose a baseball game after they realize they hate the sport and don't want to play for the whole summer.
Butters is convinced that he has the ability to communicate with the dead, but his parents try to calm him down by telling him that isn't possible as ghosts don't exist. Still, Butters realizes that if he doesn't get rid of the ghost, he is doomed to be institutionalized forever.
Jimmy realizes that he can't control his erections as the talent show approaches at South Park Elementary and fears he won't be able to do his comedy bit. He quickly sets out to curtail the problem in hopes that he'll be able to go on with the show.
The town of Beaverton, right next door to South Park, is flooded when the local beaver dam breaks. The residents of South Park don't realize that Cartman and Stan are at fault for the flooding and begin to assign their own blame as they await the appearance of rescue crews.
The boys decide to crash a 4th grade girls' sleepover to unravel the mystery of what goes on, and elect Butters to be the one to fake his own death then go in undercover as a girl.
Ms. Garrison tries to stop her one true love, Mr. Slave, from marrying his same-sex partner by leading a protest that will convince the governor not to legalize gay marriage.
Cartman suddenly acquires Gingervitis, a physical manifestation of red hair, freckles and pale skin. Tired of being insulted for his new features, he decides to unite all the "ginger kids" to rise up against their narrow-minded tormentors.
When Stan tries to find solace in religion, several religious leaders hone in on him as they are convinced he is the second coming, a situation which culminates with the appearance of a famous R&B artist.
The boys attempt to free a talking whale and get him back to his ocean family. They are forced to seek the assistance of an international government, however, when the cops come after them, armed and ready to bring them down.
Stan is mortified when his friends find out his dad was arrested for drunk driving. When a statue of the Virgin Mary in a nearby town begins to exhibit some miraculous bleeding, religious devotees head to the statue site hoping for a miracle of their own, as does Stan's dad, who wishes to rid himself of his alcoholism.