Samantha Best survives years of foster homes to arrive at Charles University with a new scholarship and her entire future ahead of her. Unless the school finds out what went down last night between her, that hot basketball player, and his roommate when a tragic accident occurs.
Sam's entire dorm hates her as does her professor. Kathryn's noise war turns Sam purple.
Sam decides the key to success can be found in a sorority, so she rushes Dorothy O'Sullivan's old house. But Kathryn has the same idea, and the two face off for the last spot.
A business project forces Sam to ask Devon for help. But her partner on the project, Noah, seems like he could be the perfect rebound guy.
Cynthia's having personal problems, so Sam pledges to be there for her anytime she needs it. But when Cynthia becomes too much too handle and bothers her during her dates with Devon, Sam decides she's had enough. Sam tries to set her straight, but instead pushes Cynthia over the edge.
Samatha is stressed by her exams and by discovering two dark secrets about Dorothy and Cynthia. Sam risks losing Dorothy's support after spending the night in her mansion.
Uncle Patrick abandoned Sam to the foster-care system years ago, and now he's decided to stick his face back into Sam's life. Trent doesn't trust him. Meanwhile, Kathryn's worried that she might be losing Beau to Sloane, so she decides to seal the deal by making him a videotape, for his eyes only.
Sam discovers Uncle Patrick's real reason for tracking her down. Devon tells Sam that he loves her. Trent makes his feelings clear to Sam. Kathryn's secret little tape does not stay secret.
Sam struggles with telling Devon that she kissed Trent. Devon is extremely jealous, and it gets worse when she spends the night locked in a room with Trent.
Sam sheds some clothing and some dignity trying to win a trip to Cabo.
Trent helps Sam get information about her family's background. Trent seems like perfect boyfriend material, until Sam meets his family and discovers his secret. Professor Fisher learns who ruined his marriage.
The biggest night of the year at Charles U. could be disastrous for Sam, when she finds herself broke, unemployed, and on her way out for good. Just when Sam needs Dorothy the most, Alicia and Uncle Patrick open Sam's eyes to the dark truth about her benefactor. Meanwhile, Kathryn decides to give Beau one last chance - a chance he proves he doesn't deserve.
Sam becomes so preoccupied with reconnecting with her birth mother that she might let both of the guys in her life slip away.