A versatile actress known for her squeaky voice, sharp comic timing and sultry good looks, Leslie Mann started her career off in commercials before segueing into films, making her big-screen debut with a bit part in the raunchy teen sex romp, "Virgin High" (1991). A one-time regular on the short-lived medical drama, "Birdland" (ABC, 1994-95), Mann bounced between genres, but never strayed too far from her comedic roots, thanks in large part to her marriage to Hollywood's comedy wunderkind, writer-director Judd Apatow, following their meeting on "The Cable Guy" (1996). In fact, it was her husband who cast her so memorably as the drunken girl who attempts to drive home intoxicated after picking up Steve Carell at a bar in "The 40-Year-Old Virgin" (2005), leaving a series of smashed cars and decapitated mailboxes in her wake, which helped elevate the actress' profile considerably. She also shined as the married older sister to Katherine Heigl in Apatow's "Knocked Up" (2007) - a role she later reprised in the critically praised "This Is 40" (2012) - before landing supporting parts in films like "Funny People" (2009), "I Love You Phillip Morris" (2011) and "The Change-Up" (2011). Whether starring for her husband or another director, Mann always brought impeccable comic timing and a willingness to do just about anything for a laugh to every one of her films.